中国实用儿科杂志

中国实用儿科杂志 ›› 2011, Vol. 26 ›› Issue (02): 131-.

• 论著 • 上一篇    下一篇

儿童阻塞性睡眠呼吸暂停低通气综合征血氧饱和度变化分析

  

  1. 首都儿科研究所附属儿童医院呼吸科，北京　100020
  • 出版日期:2011-02-06 发布日期:2011-03-03

Changes of oxygenation in children with obstructive sleep apnea hypopnea syndrome.　　

  1. Pulmonary Department of Capital Institute of Pediatrics，Beijing 100020，China
  • Online:2011-02-06 Published:2011-03-03

摘要：

研究阻塞性睡眠呼吸暂停低通气综合征（OSAHS）儿童血氧饱和度（SpO2）的变化。方法　选择于2009年7月至2010年3月因存在打鼾、睡眠张口呼吸、睡眠憋气或呼吸暂停等睡眠呼吸相关问题，在首都儿科研究所附属儿童医院进行整夜睡眠监测的141例患儿，以呼吸暂停低通气指数（AHI） > 5作为OSAHS诊断标准，将入组儿童分为OSAHS组（78例）和非OSAHS组（63例），比较两组血氧指标、OSAHS儿童快速眼动期（REM期）和非快速眼动期（NREM期）的血氧指标。结果　OSAHS组和非OSAHS组相比，最低SpO2和氧减指数（ODI）差异具有统计学意义（Z = -3.64，-5.67，P < 0.01），平均SpO2两者相比差异无统计学意义（Z =-0.90，P > 0.05）。OSAHS组REM期和NREM期相比，ODI和每小时氧减事件时间差异存在统计学意义（Z = -5.568，-5.937，P < 0.05），平均SpO2、最大氧减百分比和最长氧减时间差异无统计学意义（t = 0.364，1.868，t = -0.33，P > 0.05）。结论　OSAHS儿童存在SpO2的下降，而且REM期同NREM期相比，SpO2下降频率高，持续时间长。

关键词: 儿童, 阻塞性睡眠呼吸暂停综合征, 血氧饱和度

Abstract:

To explore the changes of oxygenation in children with obstructive sleep apnea hypopnea syndrome（OSAHS）. Methods　A total of 141 children in Capital Institute of Pediatrics from Jul. 2009 to Mar. 2010 were included in this study. Apnea hypopnea index AHI） > 5 was the diagnostic criterion for children with OSAHS. The children were divided into OSAHS group and non-OSAHS group. We compared the oxygenation indexes between OSAHS group and non-OSAHS group and between NREM period and REM period in OSAHS group. Results　There were significant differences in nadir pulse oxygen saturation（SpO2） and oxygen desaturation index（ODI） between OSAHS group and non-OSAHS group （Z = -3.64 and-5.67，P < 0.01）. There was no significant difference in mean SpO2 between OSAHS group and non-OSAHS group（Z = -0.90，P > 0.05）. There were significant differences in ODI and desaturation time per hour between rapid eye movement（REM） period and non-rapid eye movement（NREM） period in OSAHS group（Z = -5.568，Z = -5.937，P < 0.05）. There were no significant differences in maximum oxygen desaturation and maximum oxygen desaturation time between REM period and NREM period in OSAHS group（t = 0.364，t = 1.868，t = -0.33，P > 0.05）. Conclusion　Oxygen desaturation happens in children with OSAHS， and frequency of oxygen desaturation is higher and time of oxygen desaturation is longerin in REM period thand in NREM period.

Key words: children, obstructive sleep apnea hypopnea syndrome（OSAHS）, blood oxygen saturation