中国实用儿科杂志

中国实用儿科杂志 ›› 2025, Vol. 40 ›› Issue (11): 890-894.DOI: 10.19538/j.ek2025110603

• 专题笔谈 • 上一篇    下一篇

胶囊内镜在儿童Peutz-Jeghers综合征中的应用

  

  1. 中南大学湘雅医学院附属儿童医院  湖南省儿童医院，湖南  长沙  410007
  • 出版日期:2025-11-06 发布日期:2025-12-11
  • 通讯作者: 赵红梅，电子信箱：364875977@qq.com
  • 基金资助:
    湖南省卫健委重大科研专项（Z2023061）

Application of capsule endoscopy in pediatric Peutz-Jeghers syndrome

  1. The Affiliated Children’s Hospital of Xiangya School of Medicine，Central South University（Hunan Children’s Hospital），Changsha  410007，China
  • Online:2025-11-06 Published:2025-12-11

摘要： Peutz-Jeghers综合征（Peutz-Jeghers syndrome，PJS）是一种常染色体显性遗传性疾病，主要表现为皮肤黏膜色素沉着及胃肠道多发错构瘤性息肉，发病率为1/20万~1/5000。儿童期PJS息肉反复生长常致多次内镜干预，严重影响患儿生长发育。随着视频胶囊内镜（video capsule endoscopy，VCE）等检查方式的广泛应用，可实现对息肉的早期发现和干预，有助于降低儿童消化道出血及肠套叠的发生风险。该文通过系统性评价，探讨VCE在儿童PJS息肉筛查与随访中的作用，为优化PJS诊疗路径提供循证依据。

关键词:

Abstract: Peutz-Jeghers syndrome（PJS）is an autosomal dominant inherited disorder characterized by mucocutaneous pigmentation and multiple hamartomatous polyps in the gastrointestinal tract，with an incidence ranging from 1/200，000 to 1/5，000.In childhood，the recurrent growth of PJS polyps often necessitates multiple endoscopic interventions，significantly affecting the growth and development of affected children.With the widespread use of diagnostic methods such as video capsule endoscopy（VCE），early detection and intervention of polyps have become achievable，which helps to reduce the risks of gastrointestinal bleeding and intussusception in children.This review aims to explore the role of VCE in polyp screening and follow-up in pediatric PJS through systematic summary，providing evidence-based support for optimizing the diagnostic and therapeutic pathways for this condition.

Key words: