中国实用儿科杂志

中国实用儿科杂志 ›› 2023, Vol. 38 ›› Issue (10): 735-740.DOI: 10.19538/j.ek2023100604

• 专题笔谈 • 上一篇    下一篇

儿童青少年肥胖合并高尿酸血症的评估及营养管理

  

  1. 郑州大学附属儿童医院  河南省儿童医院内分泌遗传代谢科，河南  郑州  450052
  • 出版日期:2023-10-06 发布日期:2023-09-27
  • 通讯作者: 卫海燕，电子信箱：haiyanwei2009@163.com

Evaluation and nutritional management of child and adolsecent obesity with hyperuricemia

  1. Department of Endocrine，Genetics and Metabolism，Children’s Hospital Affiliated to Zhengzhou University，Zhengzhou  450052，China
  • Online:2023-10-06 Published:2023-09-27

摘要： 肥胖是继发性高尿酸血症的重要风险因素。随着肥胖患病率增高，高尿酸血症也随之明显增多且呈现低龄化趋势。儿童青少年起病的高尿酸血症称为早发型高尿酸血症。与成年患病者相比，早发型高尿酸血症更容易出现肾功能不全和痛风，且与高血压、高脂血症、胰岛素抵抗等密切相关，导致心血管疾病风险增加，因此，儿科医生应当提高对高尿酸血症的关注。高尿酸血症病因众多，国内外诊断截断值存在差异，与年龄、性别有关，需要谨慎评估。营养管理是防治高尿酸血症的基石，采用低嘌呤、低脂、低盐、低果糖及高果蔬、适量谷物的饮食结构及积极的生活方式是防治青少年肥胖及高尿酸血症的重要手段。

关键词: 肥胖, 青少年, 高尿酸血症, 痛风, 营养管理

Abstract: Obesity is an important risk factor for secondary hyperuricemia. With the increase of the prevalence of obesity，hyperuricemia has also increased significantly and showed a trend of younger age. Hyperuricemia in children and adolesc-ents is called early-onset hyperuricemia. Compared with adult patients，early-onset hyperuricemia is more prone to renal insufficiency and gout，which is closely associated with hypertension，hyperlipidemia and insulin resistance，leading to the increase of cardiocerebrovascular diseases. Therefore，pediatricians should pay more attention to hyperuricemia. The etiology of hyperuricemia is complex. The cut-off value of blood uric acid for the diagnos of hyperuricemiais is different at home and abroad，and it is related to age and gender，which needs to be evaluated carefully. Nutritional management is the cornerstone of the prevention and treatment of hyperuricemia.The diet of low purine，low fat，low salt，low fructose，high fruits and vegetables and moderate grain and active lifestyle are important means to prevent and treat adolescent obesity and hyperuricemia.

Key words: obesity, adolescents, hyperuricemia, gout, nutri-tion management