中国实用儿科杂志

中国实用儿科杂志

• 专题笔谈 • 上一篇    下一篇

儿童癫痫共患双向情感障碍

  

  1. 首都儿科研究所附属儿童医院神经内科，北京  100020
  • 出版日期:2017-04-06 发布日期:2017-03-31

Bipolar disorder comorbidity among children with epilepsy

  1. Department of Neurology，Children’s Hospital，Capital Institute of Pediatrics，Beijing  100020，China
  • Online:2017-04-06 Published:2017-03-31

摘要：

癫痫与双向情感障碍（BD）同为反复发作性的慢性脑功能障碍， 二者具有相似的临床特征及病理机制， 围癫痫发作期的情感表现与BD发作期症状临床鉴别诊断是一个难点。研究表明二者互为共患因素， 可能存在潜在的共存机制如遗传学病因， 且均对患者的生活质量及社会预后造成负面影响， 应重视共患情绪障碍如BD的评估及管理。

关键词: 癫痫, 双向情感障碍, 共患, 儿童

Abstract:

Epilepsy and bipolar disorder are common and chronic episodic disorders of brain function. Both conditions share clinical features and possible underlying pathophysiology，such as their episodic nature and potential to run a chronic course，which is difficult for clinician to make a differential diagnosis. Both disorders show epidemiological links，share some genetic etiology，and have negative impact on the quality of life and the social prognosis，so the evaluation and management of comorbid bipolar disorders in children with epilepsy should be paid attention to.

Key words: epilepsy, bipolar disorder, comorbidity, child