出版日期:
2014-12-01
发布日期:
2014-12-19
通讯作者:
庄辉(北京大学医学部病原生物学系和感染病中心);翁心华(复旦大学附属华山医院感染科)
Experts attending the discussion on long-treatment of chronic hepatitis B.
Online:
2014-12-01
Published:
2014-12-19
摘要:
核苷和核苷酸类药物(NAs)已成功用于慢性乙型肝炎(CHB)治疗。目前一致认为,乙型肝炎病毒(HBV)复制是肝损伤和疾病进展的关键因素,因此CHB治疗的主要目的是最大限度地持续抑制HBV复制。现已证明,应用NAs长期治疗CHB可明显改善肝脏组织学、逆转肝纤维化或肝硬化,以及减少肝细胞癌的发生。本文对CHB长期治疗的必要性、临床获益及管理进行了综述。
中图分类号:
参加慢性乙型肝炎长期治疗讨论会专家. 核苷和核苷酸类药物治疗慢性乙型肝炎的长期性[J]. 中国实用内科杂志, DOI: 10.7504/nk2014110301.
Experts attending the discussion on long-treatment of chronic hepatitis B.. Long-term treatment of chronic hepatitis B[J]. Acta Metallurgica Sinica, DOI: 10.7504/nk2014110301.
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