Abstract:

Now precision medicine is widely concerned. With the proposing of precision medicine，we should develop individualized treatment programs for orthodontic orthognathic patients with skeletal classⅢ malocclusion. In addition to paying attention to skeletal abnormalities，we should consider TMJ，periodontium，and upper airway through digital technique，and carry out individualized presurgery orthodontics. Based on the characteristics of TMJ，periodontium，and upper airway in skeletal class Ⅲ malocclusion，this paper explains the problems during treatment planning and briefly describes the surgery-first approach.

Key words: precision medicine, skeletal class Ⅲ, orthodontic orthognathic treatment

摘要：

目前精准医疗备受关注。随着口腔精准医学的提出，临床医生应针对骨性Ⅲ类错牙合正畸正颌联合治疗患者制定更加个性化的诊疗方案。在关注骨骼位置形态异常的同时，应结合数字化手段，对患者关节、牙周、呼吸道进行全方位的考量，进行个性化的术前正畸。文章结合骨性Ⅲ类错牙合患者的关节、牙周及呼吸道特点，讨论在制定矫治方案及治疗过程中应注意的问题，并对手术优先的方法进行阐述。

关键词: 精准医疗, 骨性Ⅲ类错牙合, 正畸正颌联合治疗