Abstract:

Objective    To explore the responses of patients with all types of burning mouth syndrome to low-level laser therapy. Methods    Totally 90 BMS patients were randomly divided into 3 groups，30 cases in each group. Group A and B were treated with low-level laser， and therapeutic regimens were one time a day for continuous irradiation of 20 days（group A）， and every other day for ten times（group B）， respectively. Group C was treated with non-irradiation light， one time a day for continuous irradiation of 20 days. Group A， B and C were all given routine medication. Before and after the treatment and in the one-month follow-up， the pain （VAS score） and the total effective rates were measured. Results    Statistically significant difference （P＜0.05） was found between group A and B in the change of VAS after treatment， and the total effective rates of group A and B were significantly higher than that of group C. The total effective rate of type 2 BMS was significantly higher than that of type1 and 3. There was no significant difference among groups and types of BMS in the VAS scores and the total effective rates between one-month follow-up and after the treatment （P＞0.05）. Conclusion    Low-level laser is effective in the treatment of BMS， especially for type 2. In a certain period of time， there is no difference in the effect with different irradiation times under the same irradiation dose parameters.

Key words: low-level laser； burning mouth syndrome, BMS； treatment

摘要：

目的    探讨低能量激光治疗各型灼口综合征（burning mouth syndrome， BMS）的疗效差异情况。方法    对2015年9月至2016 年5 月中国医科大学附属口腔医院口腔急诊·黏膜病科收治的90例各型BMS患者，随机分为3组，每组30例。在常规药物治疗基础上分别采用低能量激光治疗，每天照射1次，连续照射20 d（A组）；低能量激光治疗，隔天照射1次，共照射10次（B组）；安慰性光照射治疗，每天照射1次，连续照射20 d（C组）。比较3组患者治疗前后及随访期的疼痛改善情况［视觉模拟评分法（VAS）评分］和不同治疗时期的疗效。结果    治疗后，A、B组患者的VAS评分均有下降趋势，下降程度与C组相比，差异有统计学意义（P＜0.05）；治疗结束时，2型BMS患者与1、3型比较，疗效差异有统计学意义（P＜0.05）。1个月随访时，3组患者及BMS各分型的VAS评分和疗效与治疗结束时比较，差异无统计学意义（P＞0.05）。结论    低能量激光治疗BMS有效，且治疗2型BMS疗效优于其他分型；一定时间范围内，在照射剂量参数不变情况下，照射次数不同，疗效差异无统计学意义。

关键词: 低能量激光, 灼口综合征, 治疗