中国实用口腔科杂志

中国实用口腔科杂志

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iRoot SP和AH Plus糊剂用于根管治疗效果的Meta分析

王静a，李秀娥a，奚擎b，张琳b，刘玲b，息思扬c，吴君b   

  1. 1. 北京大学口腔医院 a 护理部，b特诊科，c牙周科，北京  100081
  • 出版日期:2017-09-15 发布日期:2017-11-22

  • Online:2017-09-15 Published:2017-11-22

摘要：

目的    系统评价iRoot SP和AH plus糊剂用于根管治疗的效果。方法    检索MEDLINE、EMBASE、Cochrane library、CNKI、万方、维普6个医学数据库，时间范围为自建库至2017年2月。由2名评价员独立筛选、评价文献和提取数据。对无异质性的文献进行Meta分析。结果    共纳入7篇文献（包含493颗患牙）。Meta分析结果显示：iRoot SP糊剂组即刻充填质量较AH Plus糊剂组高，两组比较差异有统计学意义 ［OR = 0.30，95% CI：（0.10 ~ 0.85）］；术后疼痛发生率iRoot SP糊剂组低于AH Plus糊剂组 ［OR = 0.23，95% CI：（0.06 ~ 0.89）］；在根尖渗透长度方面，iRoot SP糊剂组短于AH Plus糊剂组 ［WMD = -0.13，95%CI：（-0.22 ~ -0.05）］。结论    iRoot SP糊剂用于根管治疗中可以缓解患者疼痛，远期疗效好，生物相容性较好，是理想的根管充填材料。 由于本研究中纳入分析的文献较少且均为国内文献，因此有必要进一步开展大样本、多中心、随机、双盲的对照试验来验证结论。

关键词: AH Plus, iRoot SP, 根管治疗, Meta 分析

Abstract:

Objective    To systematically evaluate the effect of iRoot SP and AH Plus paste in the treatment of root canal. Methods    Online databases including PubMed，EMBASE，the Cochrane Library，Web of Knowledge，and Chinese databases （Wanfang database，VIP and CNKI） were searched systematically up to February 2017. Randomized controlled trials and high-quality comparative studies were considered eligible for inclusion. Two qualified reviewers reviewed the original articles，evaluating qualities of articles，and extracting data independently. After heterogeneity test，Meta-analysis was performed. Results    In total，seven original clinical controlled trials were included，containing 493 teeth. iRoot SP paste could improve the immediate root canal quality ［OR=0.30，95%CI：（0.10 ~ 0.85）］，reduce the rate of postoperative pain ［OR=0.23，95%CI：（0.06 ~ 0.89）］，and decrease the apical leakage ［WMD=-0.13，95%CI：（-0.22 ~ -0.05）］. Conclusion    iRoot SP paste in root canal therapy can significantly alleviate pain，and the long-term curative effect is good，has better biological compatibility，which is an ideal root canal filling material. Because of the small number of the literatures included，which are all in China，it is necessary to include large sample，multicenter，randomized，double-blind，placebo-controlled trails to further confirm the clinical effect.

Key words: AH Plus, iRoot SP, root canal treatment, Meta analysis