中国实用儿科杂志

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基于电子数据采集系统在川崎病临床研究中的应用

  

  1. 上海交通大学附属儿童医院心内科,上海  200062
  • 出版日期:2017-08-06 发布日期:2017-07-28

Application of the electronic data capture system in clinical research of Kawasaki disease

  1. Department of Cardiology,Shanghai Children’s Hospital,Shanghai Jiao Tong University,Shanghai  200062,China
  • Online:2017-08-06 Published:2017-07-28

摘要:

川崎病(Kawasaki disease, KD)是一种病因未明的好发于5岁以下儿童的全身性血管炎性疾病, 流行病学调查显示, 日本发病率最高, 其次是韩国和中国, 亚裔人群发病率高于非亚裔人群。许多国家均进行过KD的全国性流行病学调查,目前中国尚缺乏这一疾病的大样本多中心研究资料。应用电子数据采集(electronic data capture, EDC)系统可以快速而准确地收集和管理KD患者临床资料和实验室数据, 将该系统推广应用, 有助于为开展KD多中心研究的流行病学研究提供实时的数据来源, 从而为提出中国儿童的KD诊断、 治疗方案及制定高危因素评估指南提供循证依据。

关键词: 川崎病, 电子数据采集系统

Abstract:

Kawasaki disease is a kind of systemic vascular inflammatory disease which often occurs in children under the age of five, and the etiology is still unknown. According to the epidemiological survey, the incidence of Kawasaki disease in Japan is the highest, followed by South Korea and China. The incidence in Asian populations is higher than in non-Asian populations. Many countries have  studied the national wide epidemiological survey of Kawasaki disease, but China is still in lack of this kind of multicenter survey data about Kawasaki disease. Electronic Data Capture System can collect and manage the clinical and laboratory database of Kawasaki disease very quickly and accurately. If this system can be promoted to the whole country of China, it will can be helpful to run a multicenter study of Kawasaki disease, in order to provide evidence for making KD diagnosis,treatment plan and evaluation of the risk factors in Chinese children.

Key words: Kawasaki disease, electronic data capture system