[1] Gregory J, Feusner J. Acute promyelocytic leukemia in childhood [J]. Curr Oncol Rep, 2009, 11(6):439-445. [2] Yoo ES. Recent advances in the diagnosis and management of childhood acute promyelocytic leukemia [J]. Korean J Pediatr, 2011,54(3):95-105. [3] Sanz MA, Montesinos P, Rayon C, et al. Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome [J]. Blood, 2010, 115(25):5137-5146. [4] Ortega JJ, Madero L, Martin G, et al. Treatment with all-trans retinoic acid and anthracycline monochemotherapy for children with acute promyelocytic leukemia: a multicenter study by the PETHEMA Group [J]. J Clin Oncol, 2005, 23(30):7632-7640. [5] Huang H, Qin Y, Xu R, et al. Combination therapy with arsenic trioxide, all-trans retinoic acid, and chemotherapy in acute promyelocytic leukemia patients with various relapse risks [J]. Leuk Res, 2012, 36(7):841-845. [6] Luo XQ, Ke ZY, Huang LB, et al. Improved outcome for Chinese children with acute promyelocytic leukemia: a comparison of two protocols [J]. Pediatr Blood Cancer, 2009, 53(3):325-328. [7] Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function [J]. Cell, 2004, 116(2):281-297. [8] Kloosterman WP,Plasterk RH. The diverse functions of microRNAs in animal development and disease [J]. Dev Cell, 2006, 11(4):441-450. [9] Babashah S, Sadeghizadeh M, Tavirani MR, et al. Aberrant microRNA expression and its implications in the pathogenesis of leukemias [J]. Cell Oncol (Dordr), 2012, 35(5):317-334. [10] 罗学群,徐令,柯志勇,等. 儿童急性粒细胞白血病及其亚型的微小RNA表达[J]. 中华肿瘤杂志,2011,33(11):831-835. [11] 刘晓丹,徐令,檀卫平,等. miR-125b在儿童AML中的表达及其反义寡核苷酸对白血病细胞的作用[J]. 中国病理生理杂志,2012,28(4):738-741. [12] Gambari R, Fabbri E, Borgatti M,et al. Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development[J]. Biochem Pharmacol,2011,82(10):1416-1429. [13] Bousquet M, Quelen C, Rosati R, et al. Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation. J Exp Med, 2008. 205(11):2499-2506. [14] Bousquet M,Harris MH, Zhou B, et al. MicroRNA miR-125b causes leukemia [J]. Proc Natl Acad Sci USA, 2010, 107(50):21558-21563. [15] Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch [J]. Nat Rev Cancer, 2002, 2(9):647-656. [16] Leu JI, Dumont P, Hafey M, et al. Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex [J]. Nat Cell Biol, 2004, 6(5):443-450. [17] Perfettini JL, Kroemer RT, Kroemer G. Fatal liaisons of p53 with Bax and Bak [J]. Nat Cell Biol, 2004, 6(5):386-388. [18] Le MT, Shyh-Chang N, Khaw SL, et al. Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs [J]. PLoS Genet, 2011, 7(9):e1002242. [19] Le MT, Teh C, Shyh-Chang N, et al. MicroRNA-125b is a novel negative regulator of p53[J]. Genes Dev, 2009, 23(7):862-876. [20] Foulkes WD. p53-master and commander [J]. N Engl J Med, 2007, 357(25):2539-2541. [21] Jamieson K, Odenike O. Late-phase investigational approaches for the treatment of relapsed/refractory acute myeloid leukemia [J]. Expert Opin Pharmacother, 2012, 13(15):2171-2187. [22] Shaffer BC, Gillet JP, Patel C, et al. Drug resistance: still a daunting challenge to the successful treatment of AML [J]. Drug Resist Updat, 2012, 15(1-2):62-69. [23] Chauhan PS,Bhushan B, Singh LC, et al. Expression of genes related to multiple drug resistance and apoptosis in acute leukemia: response to induction chemotherapy [J]. Exp Mol Pathol, 2012, 92(1):44-49. [24] Weisberg E,Sattler M,Ray A,et al. Drug resistance in mutant FLT3-positive AML [J]. Oncogene, 2010, 29(37):5120-5134. [25] Weisberg E,Barrett R,Liu Q,et al. FLT3 inhibition and mechanisms of drug resistance in mutant FLT3-positive AML [J]. Drug Resist Updat, 2009, 12(3):81-89. [26] Baran Y, Gur B, Kaya P, et al. Upregulation of multi drug resistance genes in doxorubicin resistant human acute myelogeneous leukemia cells and reversal of the resistance [J]. Hematology, 2007, 12(6):511-517. [27] Styczynski J. Drug resistance in childhood acute myeloid leukemia [J]. Curr Pharm Biotechnol, 2007, 8(2):59-75. [28] Bai H, Xu R, Cao Z, et al. Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line[J]. FEBS Lett,2011,585(2):402-408. [29] Liu L,Wang S,Chen R, et al. Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562[J]. Biochem Biophys Res Commun,2012,425(2):368-373. [30] Feng DD,Zhang H,Zhang P,et al. Down-regulated miR-331- 5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia [J]. J Cell Mol Med, 2011, 15(10):2164-2175. |