中国实用儿科杂志

中国实用儿科杂志

• 专题笔谈 • 上一篇    下一篇

儿童幽门螺杆菌感染规范化治疗

  

  1. 复旦大学附属儿科医院消化科，上海  201102
  • 出版日期:2016-07-06 发布日期:2016-07-08

Standardized treatment for Helicobacter pylori infection in children

  1. Department of Gastroenterology，Children’s Hospital of Fudan University， Shanghai  201102， China
  • Online:2016-07-06 Published:2016-07-08

摘要：

幽门螺杆菌（Hp）治疗可减少儿童Hp相关性胃炎、 消化性溃疡的复发。儿童中常用的Hp一线治疗方案是以质子泵抑制剂（PPI）联合2种抗生素的三联疗法。但由于耐药菌株、 患者依从性等问题的存在， Hp根除率逐年下降。根除儿童Hp需个性化治疗。

关键词: 幽门螺杆菌, 质子泵抑制剂, 序贯疗法, 微生态

Abstract:

It is well known that a successful eradication of H.pylori dramatically reduces the rate of recurrence of gastritis and peptic ulcers in affected children. The recommended first-line eradication therapy for H.pylori infection has been triple therapy consisting of a proton pump inhibitor and two antibiotics. However，the eradication rate has declined in recent years，due to an increased bacterial resistance to antibiotics or decreased compliance with the patients. The treatment of H.pylori infection in children should be personalized.

Key words: Helicobacter pylori, proton pump inhibitor, sequential therapy, microecology