关键词: 胰腺导管内乳头状黏液性肿瘤, 指南, 风险因素, 手术原则

Abstract: Interpretation of the Updated Clinical Practice Guidelines for Intraductal Papillary Mucinous Neoplasm of the Pancreas (2023 edition)        PU Ning, LIU Liang, LOU Wen-hui, et al. Zhongshan Hospital, Fudan University, Shanghai 200032, China
Corresponding author: WU Wen-chuan, E-mail: wu.wenchuan@
zs-hospital.sh.cn
Abstract    Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is one of the main precursor lesions to pancreatic cancer, and prompt surgical intervention is necessary once malignant transformation is suspected. On July 7, 2022, the 26th International Symposium on Pancreatic Diseases was held in Kyoto, Japan, during which a meeting was conducted to discuss further revisions to the diagnosis and treatment guidelines for IPMN, resulting in the formulation of a new edition—Kyoto guidelines. The new edition systematically evaluates evidence collected on five main themes: revision of high-risk stigmata and worrisome features, principles of follow-up for non-surgically resected IPMN, follow-up principles for surgically resected IPMN, revisions in pathology, and research on cyst fluid molecular markers. 

Key words: intraductal papillary mucinous neoplasm, guidelines, risk factor, operative principle