关键词: 消化道肿瘤, 新辅助治疗, 影像组学, 疗效评估

Abstract: Advances in radiomics research on efficacy evaluation of neoadjuvant therapy for gastrointestinal cancer        LI Jia-zheng, TANG Lei. Department of Radiology, Peking University Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, China
Corresponding author: TANG Lei，E-mail:tangl@bjcancer.org
Abstract    Radiologic metrics are reliable biomarkers for evaluating the efficacy of neoadjuvant therapy in the context of digestive system cancer. Radiomics is an emerging field that combines artificial intelligence with medical images. Radiomics models could be built to support clinical decision-making by extracting and combining the vast amount of information embedded in the images, such as morphologic features, texture features, and high-dimensional features of the region of interest. It has great potential for evaluating responses precisely. Some encouraging radionics research results have been published. Affected by inter-model heterogeneity and complexity factors, as well as the lack of high-level evidence studies required for clinical application, clear clinical translation has not yet been achieved. The application of radiomics in evaluating the efficacy of neoadjuvant therapy for gastrointestinal cancer needs rigorously designed multi-center，large-sample clinical studies and prospective verification to provide effective evidence for the routine clinical application of this innovative method.

Key words: digestive tract neoplasms, neoadjuvant therapy, radiomics, efficacy evaluation