中国实用外科杂志

中国实用外科杂志 ›› 2021, Vol. 41 ›› Issue (11): 1262-1268.DOI: 10.19538/j.cjps.issn1005-2208.2021.11.15

• 论蓍 • 上一篇    下一篇

年轻女性早期乳腺癌病人生育相关调查研究

吴克瑾，陈玉芸，金玉春，张    鹏，安    培   

  1. 复旦大学附属妇产科医院乳腺科，上海 200011
  • 出版日期:2021-11-01 发布日期:2021-11-08


  • Online:2021-11-01 Published:2021-11-08

摘要： 目的    了解年轻女性乳腺癌病人的生育现状。 方法    以2018年11月至2021年1月在复旦大学附属妇产科医院乳腺外科门诊就诊的226例女性乳腺癌病人为研究对象，采用问卷调查对病人年龄、婚姻状况、生育史、生育计划及生育力保存等资料进行观察分析。 结果    226例病人中，≤40岁且无远处转移者占63.27%（143/226），143例病人中，未婚未育乳腺癌病人更倾向于有生育意愿。年龄、婚姻状况、生育史、乳腺癌分子分型是乳腺癌诊断时“是否与医师讨论生育功能保留问题”、“是否担心药物治疗会影响生育功能”、“是否与医师讨论改变药物治疗方案”、“是否采取生育功能保留措施”的关键影响因素（P值均＜0.05）。 结论    未婚未育的年轻女性乳腺癌病人有更高的生育需求，乳腺外科医师要增加对癌症病人生育力保存的知识储备，抗癌治疗前充分了解病人的生育需求，及时启动乳腺癌病人生育力保存的多学科诊疗。

关键词: 年轻女性, 乳腺癌, 生育, 问卷调查

Abstract: Investigation on fertility of young women with early breast cancer        WU Ke-jin, CHEN Yu-yun, JIN Yu-chun, et al. Department of Breast Surgery, Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China
Corresponding author:WU Ke-jin,E-mail：kejinwu@163.com
Abstract    Objective    To investigate the fertility status of young women with breast cancer. Methods    A total of 226 female patients with breast cancer who visited the Breast Surgery Department of Obstetrics and Gynecology Hospital of Fudan University from November 2018 to January 2021 were selected as the research subjects. The data of age, marital status, fertility history, fertility plan and fertility preservation of the patients were collected by questionnaire. Results  Among the 226 patients, 63.27% (143/226) were under 40 years old without distant metastasis, 143 patients were finally included.  Unmarried and childless breast cancer patients had greater desire for fertility. Age, marital status, fertility history and molecular subtypes of breast cancer are the key influencing factors of "whether to discuss fertility preservation with physicians", "whether to worry about medication might affect fertility function", "whether to discuss with physicians about changing drug therapy to protect fertility function", "whether to use fertility preservation measures" (P<0.05). Conclusion    Unmarried and childless young breast cancer patients  have higher fertility demand. Breast surgeons should increase knowledge on fertility preservation of cancer patients, fully understand the fertility needs of patients as much as possible before anti-cancer treatment, and timely start the multidisciplinary diagnosis and treatment of fertility preservation of breast cancer patients.

Key words: young woman, breast cancer, fertility , questionnaire survey