关键词: 腹腔镜胃袖状切除术, 肥胖, 代谢疾病, 十二指肠-空肠旁路术, 空肠旁路术

Abstract: Evaluation of the clinical application of derived procedures based on laparoscopic sleeve gastrectomy                WANG Yong，SHEN Ming-yang. Department of General Surgery，the Fourth Affiliated Hospital of China Medical University，Shenyang 110032，China
Corresponding author：WANG Yong，E-mail：wangyong@cmu.edu.cn
Abstract    Laparoscopic sleeve gastrectomy (LSG) is the most widely performed weight-loss surgery，but there are also various problems，such as unsatisfactory weight loss effect in some patients，poor  effect of improving hyperglycemia，or chronic gastric leakage，reflux esophagitis and other complications. In order to pursue a better effect of weight loss and the higher remission rate of metabolic diseases，a variety of derivative surgeries were developed based on LSG. For example，mini gastric bypass/one anastomosis gastric bypass (MGB/OAGB)，laparoscopic sleeve gastrectomy with jejunal-jejunal bypass(LSG-JJB)， laparoscopic sleeve gastrectomy with duodenal-jejunal bypass (LSG-DJB)，single-anastomosis duodenal-ileal bypass with sleeve gastrectomy（SADI-S），etc. However，the clinical outcomes of these procedures have not been supported by the data of multi-center prospective studies. The improvement and development of these methods have promoted the understanding of metabolic diseases by bariatric and metabolic surgeons，and provided alternative options for clinical treatment of obesity and diabetes.

Key words: laparoscopic sleeve gastrectomy, obesity, metabolic disease, duodenal-jejunal bypass, jejunal-jejunal bypass