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《英国肝硬化病人静脉曲张出血治疗指南》解读

盛基尧张学文   

  1. 吉林大学白求恩第二医院肝胆胰外科,吉林长春130041
  • 出版日期:2016-12-01 发布日期:2016-12-01

  • Online:2016-12-01 Published:2016-12-01

摘要:

食管及胃静脉曲张出血是肝硬化病情进展过程中最为凶险的并发症之一,随着相关医疗技术及药物的应用,出血病人的病死率显著下降。但是,如何规范、科学的对出血病人实施个性化综合治疗,以最大程度地改善病人预后,成为一项重要的循证医学研究课题。2000年英国胃肠病学会根据当时已发表的相关系统评价文章及临床研究结果制定了《英国肝硬化病人静脉曲张出血治疗指南》,具有重要的临床治疗指导意义并得到了广泛的应用,2015年英国胃肠病学会结合近年来的基础及临床研究结果,更新了指南中的部分内容。

关键词: 肝硬化, 静脉曲张出血, 治疗指南

Abstract:

Interpretations of UK guidelines on the management of variceal haemorrhage in cirrhotic patients        SHENG Ji-yao,ZHANG Xue-wen. Department of Hepatobiliary and Pancreas Surgery, Second Hospital of Jilin University, Changchun 130041, China
Corresponding author:ZHANG Xue-wen, E-mail:zxw515@sohu.
com
Abstract    Variceal haemorrhage is one of the most dangerous complications during the progression of cirrhosis. With the application of the relevant medical technology and drugs, the mortality of hemorrhage decreased significantly. However, how to decide the individualized comprehensive treatment for patients with variceal haemorrhage , which can maximize improve patients’ prognosis, has become an important topic of evidence-based medicine. In 2000, the British Society of Gastroenterology published UK guidelines on the management of variceal haemorrhage in cirrhotic patients which was based on the published systematic reviews and clinical studies,it has an important clinical significance and has been widely used. In 2015 the British Society of Gastroenterology combined basic and clinical research results in recent years and update parts of guide contents.

Key words: cirrhosis, variceal haemorrhage, guidelines on the management