关键词: 黄色肉芽肿性胆囊炎, 胆囊癌, 鉴别诊断

Abstract:

Differential diagnosis and management strategies of xanthogranulomatous cholecystitis and gallbladder carcinoma        WANG Guang-yi, SUN Xiao-dong, QIU Wei.Department of Hepatobiliary and Pancreatic Surgery, the First Bethune Hospital of Jilin University, Changchun 130021, China
Corresponding author: WANG Guang-yi, E-mail：wgymd@
sina.com
Abstract    Xanthogranulomatous cholecystitis (XGC) is a rare type of cholecystitis, and the etiopathogenesis of XGC is not fully understood. It is difficult to differentiate XGC from gallbladder carcinoma by symptoms, physical examination, laboratory tests, and radiographic findings because of uneven thickening gallbladder wall and severe adhesions with surrounding organs, especially in some cases associated with gallbladder carcinoma. Preoperative and intraoperative diagnosis rate is poor. Preoperative and intraoperative fine needle aspiration cytology and frozen pathology is important to the intraoperative surgical management. Because of a high conversion rate (laparoscopic to open cholecystectomy) and incidence of complications with laparoscopic cholecystectomy, open surgery is suggested. The appropriate surgical procedures should be performed according to intraoperative frozen pathology results.

Key words: xanthogranulomatous cholecystitis, gallbladder carcinoma, differential diagnosis