关键词: 肝细胞癌, 复发转移, 再治疗

Abstract:

Reasonable option of re-treatment approaches for recurrent hepatocellular carcinoma        XIAO Yong-sheng，ZHOU Jian. Liver Cancer Institute and Zhongshan Hospital，Fudan University，Shanghai 200032，China
Corresponding author：ZHOU Jian，E-mail：zhou.jian@
zs-hospital.sh.cn
Abstract    Recurrence and metastasis of liver cancer are the main obstacle influencing long-term survival of patients accepted curative therapy. Early detection，diagnosis and treatment of recurrent tumor should be performed for the improvement of surgical effects. According to the tumor stage，liver function，remnant liver volume and patient’s performance，multidisciplinary management approach is available for recurrent tumor including curative re-resection，salvage liver transplantation，radiofrequency ablation，trans-arterial chemoembolization，radiation therapy and systemic therapy. The meta-analysis results are the prior basis to evaluate different therapeutic strategy effect in the absence of prospective randomized controlled clinical study’s evidence.

Key words: hepatocellular carcinoma, recurrence and metastasis, re-treatment