中国实用外科杂志

中国实用外科杂志 ›› 2012, Vol. 32 ›› Issue (03): 203-205.

• 专题笔谈 • 上一篇    下一篇

肝移植治疗Caroli病及其临床评价

杨    扬，姜    楠   

  1. 中山大学附属第三医院肝移植中心 中山大学器官移植研究所，广东广州 510630
  • 出版日期:2012-03-01 发布日期:2012-02-24

  • Online:2012-03-01 Published:2012-02-24

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摘要：

1997年肝移植首次应用于Caroli病的治疗，此后陆续出现肝移植成功治疗Caroli病的报道。临床研究发现Caroli病病人肝移植术后受体与移植物的5年存活率分别可以达到76%和71%。活体肝移植在Caroli病治疗方面的应用也逐渐增多，大量的临床观察发现Caroli病病人经活体肝移植术后受体2年存活率可达81.6%。因此，对于肝内胆管扩张弥漫全肝或反复出现胆管炎、肝内胆管结石的Caroli病病人来说，肝脏移植是其最终可行的治疗手段。

关键词: Caroli病, 肝脏移植

Abstract:

Liver transplantation for Caroli’s disease and its clinical evaluation        YANG Yang, JIANG Nan. Center of Liver Transplantation, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou510630, China
Corresponding author: YANG Yang, E-mail: yysysu@163.com
Abstract    One of the earliest reports of liver transplantation (LT) for Caroli’s disease was reported by Sans in 1997, and then successful cases of LT performed in Caroli’s disease emerged. The clinical research discoverd that the 5 years survival rate of recipient and transplants can reach 76 percent and 71 percent after LT respectively. Living donor liver transplantation application in Caroli’s disease increased gradually in recent years, and its 2 years survival rate could reach 81.6 percent. Therefore, LT is a feasible option in the treatment of diffuse Caroli’s disease, even when complicated by recurrent cholangitis or intrahepatic bile duct stone.

Key words: Caroli’s disease, liver transplantation