中国实用外科杂志 ›› 2011, Vol. 31 ›› Issue (11): 1012-1015.

• 专题笔谈 • 上一篇    下一篇

胃癌肝转移新辅助治疗与手术选择

毕建威,申晓军   

  1. 第二军医大学附属长海医院外科,上海200433
  • 出版日期:2011-11-01 发布日期:2011-10-24

  • Online:2011-11-01 Published:2011-10-24

摘要:

目前,外科手术治疗仍然是胃癌肝转移(GCLM)病人的合理治疗方式之一,手术治疗后部分病人可获得长期存活。新辅助治疗包括全身化疗和经血管介入技术可以为GCLM手术治疗创造条件,从而扩大根治性手术治疗的应用范围。GCLM手术的新辅助治疗指征和疗效仍存在争议,需要经过多中心的前瞻性随机对照研究来证实。

关键词: 胃癌, 肝转移, 肝切除

Abstract:

Choice of neoadjuvant therapy and surgery in gastric cancer with liver metastases        BI Jian-wei, SHEN Xiao-jun. Department of General Surgery, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China
Corresponding  author :BI Jian-wei,E-mail:bijianwei@medmail.com.cn
Abstract    Surgery should be considered as a rational therapy for gastric cancer with liver metastases (GCLM), some of whom can survive long term after surgery. Neoadjuvant chemotherapy and transarterial therapy have been demonstrated efficient to downstage tumor and increase the curative R0 resection rate. However, the optimal indications and effective results of surgery and neoadjuvant therapy of GCLM remains a matter for debate. Therefore, further studies from multicenter, prospective, randomized trials are necessary to determine which patients will benefit from surgery of GCLM.

Key words: gastric cancer, liver metastasis, hepatectomy