关键词: Oddi括约肌, 胆石症

Abstract:

Correlation between Oddi’s sphincter abnormality and cholelithiasis        WU Shuo-dong. Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
Abstract     The etiology of cholelith is complicated with involvement of sphincter of Oddi(SO). For primary bile duct pigment stones, both duodenoscopy and barium meal revealed high incidence of periampullary diverticulum. SO manometry through “T” tube sinus showed hypomotiligy of SO. Oral intake of 99Tcm-DTPA and measurement of amylopsin-1 and enterokinase confirmed the existence of duodeno-biliary and pancreaticobiliary refluxes. Measurement of fatty acids in gallstones also suggested phospholipase A1 played a role in the formation of bile duct pigment stones. For gallbladder cholesterol stones, hypermotiligy of SO existed. SO dysfunction and recurrent of bile duct stones after cholecystectomy revealed, at least in part, some gallbladder stones were primarily caused by SO abnormality.

Key words: Oddi&rsquo, s sphincter；cholelithiasis