中国实用外科杂志

中国实用外科杂志 ›› 2009, Vol. 29 ›› Issue (12): 986-988.

• 专题笔谈 • 上一篇    下一篇

感染性休克治疗中的血糖控制及评价

侯 静，许 媛   

  1. 首都医科大学附属北京同仁医院 ICU，北京100730
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-12-18 发布日期:2009-12-18

  • Received:1900-01-01 Revised:1900-01-01 Online:2009-12-18 Published:2009-12-18

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摘要：

高血糖和胰岛素抵抗是危重病人普遍存在的临床现象，随着每日平均血糖水平升高，病人发生感染、器官功能障碍、心血管并发症及死亡等的风险均明显增加，特别是严重感染和感染性休克病人血糖升高与波动更为突出。近年来曾有单中心前瞻性对照研究表明，强化胰岛素治疗控制血糖于正常化可以降低上述并发症的发生率及死亡率，但同时又明显增加了低血糖的发生风险。此外，后期的研究在血糖控制改善预后方面的影响存在争议。

关键词: 感染性休克, 血糖控制

Abstract:

Glucose control in septic shock HOU Jing, XU Yuan.Department of Intensive Care Unit, Beijing Tongren Hospital, Affiliated Capital Medical University, Beijing 100730, China Corresponding author: XU Yuan, E-mail: xuyuan@trhos.com Abstract Hyperglycemia and insulin resistance are common in critically ill patients, and are associated with worsened outcome. Previous studies showed that intensive insulin therapy to perform glucose control reduced morbidity and mortality. However, recent multi center studies have failed to prove those findings and have occurred high risk of hypoglycemia. Based on those conflicting clinical evidences, glucose control need to be assessed.

Key words: septic shock, glucose control