中国实用外科杂志

中国实用外科杂志 ›› 2009, Vol. 29 ›› Issue (03): 226-228.

• 论著 • 上一篇    下一篇

原发性乳腺神经内分泌癌13例诊治分析

潘晓峰，毕永林，秦贤举，钱 斌   

  1. 上海市第八人民医院普外科，上海200235
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-03-13 发布日期:2009-03-13

  • Received:1900-01-01 Revised:1900-01-01 Online:2009-03-13 Published:2009-03-13

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摘要：

目的 探讨原发性乳腺神经内分泌癌的诊断和治疗策略。方法 结合文献对上海市第八人民医院普外科自1980年至今收治的13例原发性乳腺神经内分泌癌的分类、流行病学、诊断和治疗方法等进行分析。结果 13例中实体型原发性乳腺神经内分泌癌4例，小细胞型原发性乳腺神经内分泌癌5例，大细胞型原发性乳腺神经内分泌癌4，皆无腋窝淋巴结转移，总的5年无病存活率为76.9%（10/13），存活率为84.6%（11/13），病死率为15.4%（2/13）。结论 原发性乳腺神经内分泌癌的影像学诊断比较困难，诊断上的金标准是组织活检。在治疗上，参考乳腺浸润性导管癌的治疗策略对其治疗可获得较满意效果。

关键词: 乳腺癌, 神经内分泌肿瘤

Abstract:

Diagnosis and therapy of primary neuroendocrine carcinoma of breast：an analysis of 13 cases PAN Xiao-feng,BI Yong-lin,QIN Xian-ju,et al. Department of General Surgery,Shanghai the 8th People’s Hospital, Shanghai200233，China Corresponding author: BI Yong-lin，E－mail：biyonglin@163.com Abstract Objective To discuss the strategy in diagnosis and therapy of primary neur-oendocrine carcinoma of breast. Methods The definition,classification,epidemiology,diagnose and treatment were discussed in 13 cases of primary neuroendocrine carcinoma of breast treated in surgery department of Shanghai the eighth people’s hospital from 1980 to now with reviewing lectures.Results In the 13 cases,4 cases was solid neuroendocrine carcinoma,5 cases was small cell neuroendocrine carcinoma,4 cases was large cell neuroendocrine carcino-ma.All of the cases’ axillary limph node is negative.Total diseases free survival rate was 76.9%（10/13）,overal survival rage was 84.6%（11/13）.Conclusion To diagnose primary neur-oendocrine carcinoma of breast by imaging is difficult.The golden standard of diagnosis is biospy.It is acceptable to treat the patients with the guideline of invasive ductal carcinoma in breast..

Key words: breast cancer , neuroendocrine carcinoma