关键词: 凝血酶原时间, 活化部分凝血活酶时间, 凝血机制障碍

Abstract:

Clinical significance and treatment of preoperative coagulation abnormalities        MAO Yi-lei，SUN Yong-liang. Department of Liver Surgery，Peking Union Medical College Hospital，PUMC & Chinese Academy of Medical Sciences，Beijng 100730，China
Corresponding author：MAO Yi-lei，E-mail：maoy@public3.bta.net.cn
Abstract    Perioperative managements are complicated when surgical patients have coagulation disorders. Among the coagulation assays, PT and APTT are more significant in evaluating preoperative coagulation function. Surgeons may not be familiar with the management process for abnormal results from the tests (PT, APTT) in preoperative screening. In the review, the possible factors and systemic diseases affecting the tests are discussed and practical approaches in clinical management according to different abnormality are introduced. The instruction of interpreting and processing various coagulant tests is also suggested.

Key words: prothrombin time, activated partial thromboplastin time；dysfunction of blood coagulation