中国实用外科杂志

中国实用外科杂志 ›› 2006, Vol. 26 ›› Issue (06): 1-452.

• 论著 •    

Hassab术后门静脉系统血栓形成原因及预防

刘彧,梁廷波,郑树森,俞军   

  1. 浙江大学医学院附属第一医院肝胆外科，浙江杭州310003
  • 收稿日期:2006-01-20 修回日期:2006-03-10 出版日期:2006-06-20 发布日期:2006-06-20

The causes and prevention of portal vein thrombosis after the Hassab’s operation.

Liu Yu,Liang Tingbo,Zheng Shusen,et al.   

  1. Depatment of Hepatobiliary Surgery,the First Affiliated Hospital of Medical College of Zhejiang University,Hangzhou 310003,China
  • Received:2006-01-20 Revised:2006-03-10 Online:2006-06-20 Published:2006-06-20

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摘要：

目的:探讨肝硬化病人行Hassab术后门静脉系统血栓形成（PVT）的原因、诊治及预防。方法:对浙江大学医学院附属第一医院1999-2004年200例接受Hassab手术的病人进行回顾性分析。结果:26例病人发现门静脉系统的血栓形成，发病率为13%（26/200），抗凝治疗后均顺利出院，无一例死于该并发症。结论:Hassab术后并发PVT病因尚未明确，血小板峰值>300×109/L是危险因素；其诊治关键在于早期发现和及时抗凝溶栓治疗，预防性抗凝并不能明显降低发生率。

关键词: Hassab手术, PVT, 血小板峰值, 预防性抗凝

Abstract:

Objective:To discuss the pathogenesis,diagnosis,therapy,and precaution of the portal vein thrombosis (PVT) after Hassab’s operation. Methods:Two hundred patients who underwent Hassab’s operation because of liver cirrhosis with portal hypertension between 1999 and 2004 in the First Affiliated Hospital of Medical College of Zhejiang University were analyzed retrospectively. Results:Twentysix patients developed PVT after operation (13%),and all of them discharged smoothly after anticoagulant therapy. Conclusion:The definite cause of PVT after Hassab’s operation is still unclear.The peak value of plate which exceeded 300×109/L is a risk factor.The preventive anticoagulation can not decrease incidence of PVT.The key point of therapy is early diagnosis and early anticoagulant treatment.

Key words: Hassab operation, PVT, Peak value of plate, Prophylactic anticoagulation