关键词: 复杂腹腔感染, 社区获得性腹腔感染, 医院获得性腹腔感染, 艰难梭菌感染, 抗菌药物

Abstract:

Basic principles, controversy and consensus on the use of antibiotics in the treatment of abdominal infection        XU Jing，ZHANG Jing-ping.Department of Infectious Diseases，the First Hospital of China Medical University，Shenyang 110001，China
Correspondingauthor：ZHANG Jing-ping，E-mail：zjp809302@163.com
Abstract    Complicated intra-abdominal infections （cIAIs） remain a majorchallenge in clinical practice.In addition to significant morbidity and mortality for patients，they consume substantial hospitalresources. It is compounded by the aging of thepopulation and the burden of chronic disease in these patients，as well as the increased prevalence of resistantbacteria in both the healthcare setting and the community.Besides timely effective source control and fluid resuscitation，rational use of antimicrobials isanintegral part of good clinical practice.Once cIAIs are suspected or diagnosed，anti-infective treatment should be given as soon as possible.At this time，empirical anti-infective treatment is particularly important due to the lack of microbial culture and drug susceptibility results. In the process of anti-infective treatment, the application of anti-infective drugs can be adjusted according to the culture of pathogens and the results of drug sensitivity experiments.

Key words: complicated intra-abdominal infections, community-acquired intra-abdominal infections, health care-associated intra-abdominal infections, clostridium difficile infections, antimicrobials