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全腹腔镜与腹腔镜辅助远端胃癌根治术胃十二指肠吻合相关并发症Meta分析

汪旭云1郭天康2   

  1. 1 甘肃中医药大学,甘肃兰州 730000;2 甘肃省人民医院普外一科,甘肃兰州 730000
  • 出版日期:2016-09-01 发布日期:2016-08-24

  • Online:2016-09-01 Published:2016-08-24

摘要:

目的    通过分析手术相关并发症评价行胃十二指肠吻合的全腹腔镜远端胃切除术(TLDG)治疗远端胃癌的安全性和可行性。方法    计算机检索PubMed、Cochrane Library、Web of Science、Embase、中国期刊全文数据库、中国生物医学文献数据库、万方数据库,同时辅以其他检索。检索时间均从建库至2016-01-25,语种不限。收集所有比较TLDG与腹腔镜辅助远端胃切除(LADG)胃十二指肠吻合治疗远端胃癌的回顾性队列研究。由两名评价员独立按照纳入排除标准提取数据并交叉核对,采用Cochrane 协作网推荐软件RevMan5.3 版进行统计学分析。结果    最终纳入7项研究,共1929例病人。TLDG组与LADG组在术后并发吻合口漏、吻合口出血、吻合口狭窄、腹腔脓肿、肠梗阻、胃瘫和切口并发症方面的差异均无统计学意义。结论    TLDG与LADG治疗远端胃癌胃十二指肠吻合在手术相关并发症方面无明显差异,TLDG治疗远端胃癌安全可行。

关键词: 全腹腔镜, 腹腔镜胃癌, Meta分析

Abstract:

The surgery-related complications of totally laparoscopic and laparoscopic assisted distal gastrectomy with gastroduodenostomy for distal gastric cancer: A Meta analysis        WANG Xu-yun*,GUO Tian-kang. *Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China
Corresponding author:WANG Xu-yun,E-mail:wangxuyun33@163.com
Abstract    Objective    To evaluate the safety and feasibility of totally laparoscopic distal gastrectomy(TLDG)with gastroduodenostomy for distal gastric cancer by analyzing the surgery-related complications. Methods    Pubmed, Cochrane Library, Web of Science, Embase, CNKI, CBM and Wanfang Database were retrieved. At the same time,other retrieval were used in any language to collect the retrospective cohort studies about TLDG with intracorporeal gastroduodenostomy and laparoscopic-assisted distal gastrectomy with extracorporeal gastroduodenostomy (LADG) that published until January 25,2016. Data related to clinical outcomes were extracted by two reviewers independently and checked alternatively according to the inclusion and exclusion criteria. Statistical analyses were carried out by the RevMan5.3 software. Results    A total of 7 studies were included,involving about 1929 patients. The meta analysis results showed that there was no statistical significant in postoperative anastomotic leakage,anastomotic bleeding,anastomotic stenosis,abdominal abscess,intestinal obstruction,gastric paralysis as well as incision complications. Conclusion    As for the surgery-related complications,there was no significant difference between TLDG and LADG with gastroduodenostomy. So the treatment of TLDG with gastroduodenostomy for distal gastric cancer is safe and feasible.

Key words: totally laparoscopic, laparoscopy, gastric cancer, Meta-analysis