中国实用外科杂志

中国实用外科杂志

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腹腔镜与开腹胃癌根治术后肠梗阻发生率比较Meta分析

王君辅，谢    勇，胡    林，李昌荣，李红浪   

  1. 南昌大学第二附属医院胃肠外科，江西南昌 330006
  • 出版日期:2015-07-01 发布日期:2015-06-30

  • Online:2015-07-01 Published:2015-06-30

摘要：

目的    比较腹腔镜与开腹手术治疗胃癌术后肠梗阻的发生率。方法    通过PubMed、 EMBASE、OVID、 Medline、中国期刊全文数据库、万方数据发表的有关腹腔镜与传统开腹胃癌根治术后发生肠梗阻相关随机对照研究文献进行定量分析，检索时间从建库至2014年3月止，采用ReMan 5.1软件对数据进行Meta分析。
结果    按入选纳入标准，共14篇文献纳入研究，总样本量3997例，其中腹腔镜组2196例，术后发生肠梗阻18例，开腹组1801例，术后发生肠梗阻46例，合并RR=0.37，95% CI：0.23～0.62 ，提示腹腔镜组术后肠梗阻的发生率为开腹组的37%，差异有统计学意义（P＜0.01）。结论    相对于开腹胃癌手术，腹腔镜胃癌手术可以降低术后早期肠梗阻的发生率

关键词: 胃癌, 腹腔镜手术, 开腹手术, 术后肠梗阻, Meta分析

Abstract:

Comparison of the incidence of postoperative ileus following laparoscopic and open radical resection for gastric cancer: A Meta analysis        WANG Jun-fu , XIE Yong , HU Lin, et al.  Department of Gastrointestinal Surgery, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, China
Corresponding author: LI Hong-lang, E-mail: lihonglang6802@163.com
Abstract    Objective    To compare the incidence of postoperative ileus following laparoscopic and open radical resection for gastric cancer. Methods    Randomized controlled trial reports published from built this database to March 2014 were searched in the PubMed、EMBASE、OVID、Medline、China National Knowledge Infrastructure (CNKI) and Wanfang databases.Articles were identified which compared the occurrence rate of postoperative iles between laparoscopic resection and conventional open resection for gastric cancer.Data were analyzed by Rev Man5.1 software.Results    Fourteen studies including 3997 cases were analyzed. A total of 2196 cases received laparoscopic surgery, of whom 18 developed postoperative ileus. There were 1801 cases underwent open surgery, of whom 46 developed early postoperative ileus. The pooled relative risk was 0.37 with a 95％ confidence interval of 0.23-0.62. The difference was significant statistically (P＜0.01). Conclusion    Compared with open surgery, laparoscopic gastric cancer resection can reduce the incidence of postoperative early ileus.

Key words: gastric cancer, laparoscopic surgery, open surgery, postoperative ileus, meta-analysis