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低位直肠癌肛提肌外腹会阴联合切除术学习曲线研究

高志冬,王    超,申占龙,梁    斌,姜可伟,沈    凯,郭    鹏,曹    键,张    鑫,杨晓东谢启伟,王    杉,叶颖江   

  1. 北京大学人民医院胃肠外科, 北京100044
  • 出版日期:2015-12-01 发布日期:2015-12-01

  • Online:2015-12-01 Published:2015-12-01

摘要:

目的    探讨直肠癌肛提肌外腹会阴联合切除术(ELAPE)的学习曲线。方法    回顾性分析北京大学人民医院胃肠外科2012年6月至2014年10月接受ELAPE的55例直肠癌病人的临床资料,运用累积和控制图找出熟练掌握ELAPE所需要的例数,然后比较学习期和熟练期病人的手术效果。结果    累积和控制分析显示熟练掌握ELAPE所需手术例数节点为30例。熟练期(30例)较学习期(25例)手术时间[(246.6±51.1)min vs.(286.3±43.2)min]、术中出血[(146.9±76.0)mL vs. (215.7±162.9)mL]和术后进食时间[(6.0±1.0)d vs.(7.0±2.0)d]均显著减少(P<0.05)。两组术后住院时间[(19.0±8.0)d vs. (18.0±9.0)d]、淋巴结检出总数[(17.0±6.0)枚vs.(17.0±9.0)枚]、手术相关并发症发生率(24.0% vs. 40.0%)、环周切缘阳性率(4.0% vs. 3.3%)、术中穿孔发生率(0 vs. 6.7%)、手术标本质量差异无统计学意义(P> 0.05)。结论    直肠癌ELAPE的学习曲线约为30例,即可达到较熟练程度。

关键词: 直肠癌, 肛提肌外腹会阴联合切除术, 累积和控制图, 学习曲线

Abstract:

Analysis of the learning curve for extralevator abdominoperineal excision for low rectal cancer:Lessons from a single center`s experience        GAO Zhi-dong,WANG Chao,SHEN Zhan-long,et al. Department of Gastrointestinal Surgery,Peking University People’s Hospital,Beijing 100044,China
Corresponding author:YE Ying-jiang,E-mail:yeyingjiang@pkuph.edu.cn
Abstract    Objective    To evaluate the learning curve of extralevator abdominoperineal excision (ELAPE) for rectal cancer. Methods    The clinical data of 55 patients with rectal cancer performed ELAPE at Peking University People`s Hospital between June 2012 and October 2014 were analyzed retrospectively. A cumulative sum (CSCUM) analysis was used to derive the learning curve. The differences between the learning phase and the proficient phase in surgical effects were analyzed retrospectively. Results    The cumulative sum analysis revealed the degree of proficiency increased after 30 cases. Compared with learning phase(30 cases),the operative time [(246.6±51.1)min vs.(286.3±43.2)min],intraoperative blood loss[(146.9±76.0)mL vs.(215.7±162.9)mL],postoperative dieting time [(6±1)d vs.(7±2)d] in proficient phase (25 cases) decreased significantly respectively (P<0.05). The hospital stay [(19±8)d vs.(18±9)d],lymph nodes harvest [(17±6)vs.(17±9)],operation-related complications incidence (24.0% vs. 40.0%), positive circumferential resection margin (4.0% vs.3.3%),intraoperative perforation incidence (0 vs. 6.7%) and the quality of specimens had no any statistical significance (P>0.05). Conclusion    The learning process for ELAPE has a greater effect on the first 30 cases.

Key words: rectum cancer, extralevator abdominoperineal excision, cumulative sum chart, learning curve