关键词: 乳腺癌, 分子分型, 个体化治疗

Abstract:

Biological subtype of breast cancer and treatment as well as prognosis        ZHAO Yi, DENG Xin. Department of Pancreatic and Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
Corresponding author: ZHAO Yi, E-mail: zhaoy5@sj-hospital.org
Abstract    With the development of early diagnosis and comprehensive treatment for breast cancer, the incidence of breast cancer is rising. Though the mortality of breast cancer declines, it remains one of the deadly diseases for woman. The prognosis of breast cancer with the same pathology type and clinical stage differs greatly even the treatment is same. It suggests highly heterogenicity of the breast cancer. The simply TNM stage based on anatomy and histology grade is not sufficient for the current breast cancer treatment. Especially need for breast cancer biological subtype based on molecular level which can suggest the clinical behavior and guide the treatment is the current research focus. It indicates that the treatment of breast cancer has entered the age of advocating individualized treatment on the basis of the standard multidisciplinary treatment. 

Key words: breast cancer, biological subtype, individualized treatment