中国实用外科杂志

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第7版日本《胃癌治疗指南》主要更新概览

赵恩昊,朱纯超,曹    晖,张子臻   

  1. 上海交通大学医学院附属仁济医院胃肠外科,上海 200127
  • 出版日期:2025-04-01

  • Online:2025-04-01

摘要: 2025-03-15,日本胃癌学会发布了第7版《胃癌治疗指南》,在腹腔镜手术、保功能手术、扩大手术、围手术期化疗、基于新兴生物标记物的化疗、胃切除术后远期并发症、高龄病人治疗策略以及姑息性治疗手段等方面提出新的临床问题并予以更新。尤其是腹腔镜全胃切除术和食管胃结合部癌的微创手术的推荐度进一步明确且有提升,在保功能手术方面则提出了胃次全切除的新术式,但在围手术期治疗和转化治疗方面仍然缺乏较明确的推荐意见。从生物标记物检测技术和新的靶向药物的应用,到关注老年胃癌病人外科治疗、内镜治疗和化疗方案的制定,无一不体现了胃癌精准诊疗和个体化治疗的思路,而关注术后远期并发症则表明对于病人长期生存和生命质量的追求。

关键词: 胃癌, 日本胃癌学会, 指南

Abstract: On March 15th 2025, the Japan Gastric Cancer Association released the 7th edition of Japanese Gastric Cancer Treatment Guidelines. New clinical questions were raised and updated in laparoscopic surgery for gastric cancer, functional preservation surgery and extended surgery, perioperative chemotherapy, chemotherapy based on biomarkers, long-term complications after gastrectomy, treatment strategies for the elderly and palliative treatment methods. In particular, the recommendation of laparoscopic total gastrectomy and minimally invasive surgery for esophagogastric junction cancer has been further clarified and improved. In terms of function preserving gastrectomy, a new surgical method of subtotal gastrectomy has been proposed. However, there is still a lack of clear recommendations in perioperative treatment and conversion therapy. From the application of biomarker detection means and the emergence of new targeted drugs, to the attention to the strategies of surgical, endoscopic and chemotherapy protocols for elderly patients with gastric cancer, all reflect the ideas of accurate diagnosis and treatment of gastric cancer and individualized treatment, while the attention paid to postoperative long-term complications indicates the pursuit of long-term survival and quality of life for patients.

Key words: gastric cancer, Japan Gastric Cancer Association, guideline