中国实用外科杂志

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感染性胰腺坏死的微创外科处理策略、技术及评价

李    非,黄铂涵,曹    锋   

  1. 首都医科大学宣武医院普通外科 首都医科大学急性胰腺炎临床诊疗与研究中心,北京100053
  • 出版日期:2024-05-01

  • Online:2024-05-01

摘要: 急性胰腺炎是常见的外科急腹症,其发病率仍在逐年上升,带来严重的经济与社会负担。坏死性胰腺炎中约30%的病人会继发感染,发展为感染性胰腺坏死(IPN),治疗难度较大,病死率可达30%。随着微创治疗技术的发展,以微创技术为核心的“进阶”治疗策略改善了病人预后,获得多项指南一致推荐。目前针对IPN,国内有多种微创治疗方式,根据各中心报道均可取得较好疗效。但值得注意的是,IPN是一种个体差异大、存在多种并发症、治疗过程复杂、具有较高病死率的疾病。因此,有必要强调IPN微创外科的治疗策略,评估现阶段各种技术的优劣,促进微创外科理念的推广。

关键词: 感染性胰腺坏死, 微创外科, 急性胰腺炎, 治疗策略, 技术评价

Abstract: Minimally invasive surgical management strategies, techniques, and evaluation for infected pancreatic necrosis        LI Fei, HUANG Bo-han, CAO Feng. Department of General Surgery, Xuanwu Hospital Capital Medical University; & Clinical Center for Acute Pancreatitis, Capital Medical University, Beijing 100053, China
Corresponding author: LI Fei, E-mail: feili36@ccmu.edu.cn
Abstract    Acute pancreatitis (AP) is a common surgical acute abdomen with an increasing incidence rate annually, which brings significant economic and social burdens. About 30% of cases of necrotizing pancreatitis will develop secondary infections and progress to infected pancreatic necrosis (IPN), which is difficult to treat and carries mortality of up to 30%. With the development of minimally invasive treatment technology, the "step-up" approach centered on minimally invasive surgery has improved the prognosis of patients and received consistent recommendations from many guidelines. Currently, there are various minimally invasive surgical methods for IPN in China, which have achieved good efficacy according to the reports from various centers. However, it is crucial to acknowledge that IPN is a disease with considerable individual variability, multiple complications, complicated treatment processes, and high mortality. Therefore, it is necessary to emphasize the treatment strategy of minimally invasive surgery for IPN, evaluate the advantages and disadvantages of current technologies, and promote the concept of minimally invasive surgery.

Key words: infected pancreatic necrosis, minimally invasive surgery, acute pancreatitis, treatment strategy, technical evaluation