关键词: 直肠癌, 术后并发症, 吻合口狭窄, 影响因素

Abstract: A multivariate analysis of anastomotic stricture after anterior resection operation on rectal cancer        FAN Si-rao，ZHANG Hong，LIU Ding-sheng，et al. Department of Colorectal Tumor Surgery，Shengjing Hospital Affiliated to China Medical University，Shenyang 110004，China
Corresponding author：ZHANG Hong，E-mail：haojiubujian1203@sina.cn
Abstract    Objective    To investigate influential factors of anastomotic stricture after anterior resection operation on rectal cancer. Methods    The clinicopathologic data of 760 patients who visit and underwent surgical operation between January 2012 and December 2017 in Department of Colorectal Tumor Surgery，Shengjing Hospital Affiliated to China Medical University were analyzed retrospectively. The causes of anastomotic stricture were investigated with logistic regression.  Results    A total of 111 patients suffered anastomotic stricture (14.6%). Univariate analysis showed that sexual distinction (χ2=6.978，P=0.008)，temporarily ileostomy in surgery (χ2=4.015，P=0.045)，distance from anal verge (t=3.239，P=0.001) and anastomotic leak after surgery (χ2=9.721，P=0.002) were relation to anastomotic stricture. Multivariate factors showed sexual distinction (OR=1.776，95%CI 1.128-2.796，P=0.013)，distance from anal verge (OR=0.907，95%CI 0.855-0.961，P=0.001) and anastomotic leak after surgery (OR=2.255，95%CI 1.293-3.932，P=0.004) were independent factors of anastomotic stricture. Conclusion    Patients who is the male，approach anal verge and patients who had anastomotic leak after surgery likely develop anastomotic stricture.

Key words: rectal cancer, postoperative complication, anastomotic stricture, influential factor