中国实用外科杂志

• 专题笔谈 • 上一篇    下一篇

直肠前切除术后吻合口复发相关对策及其争议

姚宏伟安勇博张忠涛   

  1. 首都医科大学附属北京友谊医院普通外科 国家消化系统疾病临床医学研究中心 首都医科大学结直肠肿瘤临床诊疗与研究中心,北京 100050
  • 出版日期:2020-03-01 发布日期:2020-03-18

  • Online:2020-03-01 Published:2020-03-18

摘要: 肿瘤局部复发是直肠癌病人手术后最为重大的生存风险之一。因此,降低直肠癌根治术后的局部复发率一直是结直肠外科的主要挑战。降低吻合口复发率以及局部复发率,重点在于预防,在于原发肿瘤手术时的安全切缘以及全直肠系膜切除标本的完整性,在于围手术期肿瘤综合治疗策略的执行力度。吻合口复发以及局部复发的治疗,需要手术结合多学科综合治疗协作组(MDT)模式治疗方式。从低位前切除术(LAR)到腹会阴联合切除术(APE)手术,甚至后盆腔器官切除、全盆腔器官切除,如果能够达到R0切除,都是可选择的再次手术切除方式。如何改善病人的术后生活质量,目前尚存争议。

关键词: 直肠肿瘤, 局部复发, 吻合口复发, 多学科综合治疗协作组, 再次手术

Abstract: Treatment strategy and controversy of anastomotic recurrence after anterior resection for rectal cancer                   YAO Hong-wei,AN Yong-bo,ZHANG Zhong-tao. Department of General Surgery, Beijing Friendship Hospital, Capital Medical University;National Clinical Research Center for Digestive Diseases, & Clinical Center for Colorectal Neoplasm, Capital Medical University, Beijing 100050, China
Corresponding author: ZHANG Zhong-tao,E-mail:zhangzht@ccmu.edu.cn
Abstract    One of the most important survival risks for patients with rectal cancer is local recurrence.Therefore,reducing the local recurrence rate after radical resection of rectal cancer has always been the main challenge for colorectal surgery.To reduce the recurrence of anastomosis and local recurrence,the key lies in the prevention,in the safe resection margin of primary tumor operation and the integrity of total mesorectal resection specimen,in the implementation of perioperative comprehensive treatment strategy.The treatment of anastomotic recurrence and local recurrence requires surgery combined with multidisciplinary team mode.From LAR to APE surgery,even posterior pelvic resection and total pelvic resection,if R0 resection can be achieved,all of the procedures are the alternatives of reoperation. How to improve the postoperative quality of life of patients remains controversial.

Key words: rectal neoplasm, local recurrence, anastomotic recurrence, multidisciplinary team, reoperation