关键词: 乳腺癌, 前哨淋巴结活检, 新辅助化疗, 放疗, 保乳手术

Abstract:

Problems and treatment options of sentinel  lymph node in breast cancer        WU Di, FAN Zhi-min. Department of Breast Surgery，the First Hospital of Jilin University，Changchun 130021，China
Corresponding author: FAN Zhi-min, E-mail:fanzhimn@163.com
Abstract    Sentinel lymph node biopsy (SLNB) has been the primary care in clinically node negative breast cancer. Controversy still surrounds the SLNB of the internal mammary nodes. Because different kinds of tracer have respective  feature, surgeons should choose the suitable tracer. All blue lymph nodes and any lymph nodes at the end of a blue lymphatic channel should be removed and designated as SLNs.Clinicians should not recommend ALND for women with early-stage breast cancer who have one or two SLN metastases and will receive breast-conserving surgery with conventionally fractionated whole-breast radiotherapy.Clinicians may offer ALND for women with early-stage breast cancer with nodal metastases found on SNB who will receive mastectomy. For patients who recieved neoadjuvant chemotherapy, SLNB after neoadjuvant chemotherapy is optimal.

Key words: breast cancer, sentinel lymph node biopsy, neoadjuvant chemotherapy, radiotherapy, breast conserving surgery