中国实用外科杂志

中国实用外科杂志

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甲状腺乳头状癌中央区及颈侧区淋巴结转移相关因素探讨

卢秀波   

  1. 郑州大学第一附属医院甲状腺外科，河南郑州450052
  • 出版日期:2017-09-01 发布日期:2017-09-05

  • Online:2017-09-01 Published:2017-09-05

摘要：

甲状腺癌是内分泌系统最常见的恶性肿瘤，也是头颈部最常见的恶性肿瘤，近年来其发病率逐年增高。分化型甲状腺癌（DTC）占所有甲状腺癌的95%左右，其中，甲状腺乳头状癌（PTC）占DTC的90%以上。多数PTC生长较缓慢，但颈部淋巴结转移出现早。颈部淋巴结转移是甲状腺癌病人复发率增高和存活率降低的主要原因，因此，探讨淋巴结转移的危险因素非常重要。相关研究显示，癌灶直径、年龄、腺外侵犯、性别、BRAFV600E突变是PTC中央区及颈侧区淋巴结转移的危险因素。

关键词: 甲状腺乳头状癌, 颈部淋巴结转移

Abstract:

Correlative factors of lymph node metastasis in central region and cervical region of papillary thyroid carcinoma         LU Xiu-bo. Department of Thyroid Surgery，the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
Abstract    Thyroid cancer is the most common malignant tumor of endocrine tumors. The incidence of thyroid cancer is increasing in recent years. Differentiated thyroid carcinoma (DTC) accounts for about 95% of all thyroid cancers, with papillary thyroid carcinoma (PTC) accounting for more than 90% of DTC. Most PTCs grew slowly, but cervical lymph node metastasis occurred early. Neck lymph node metastasis is the main reasons for the high recurrence rate and low survival rate of thyroid cancer patients. Therefore, it is very important to explore the risk factors of lymph node metastasis. The article analyzed the risks of lymph nodes metastasis by reviewing the related literature. The results show that tumor diameter, age, gender, extrathyroid extension, BRAFV600E mutation are the risks factor for lymph node metastasis of lateral and central neck.

Key words: papillary thyroid carcinoma, cervical lymph node metastasis