中国实用口腔科杂志 ›› 2012, Vol. 5 ›› Issue (10): 587-591.

• 专题笔谈 • 上一篇    下一篇

口腔益生菌防龋作用与应用

王胜朝许浩坤   

  1. 作者单位:第四军医大学口腔医学院口腔预防科,西安  710032
  • 出版日期:2012-10-15 发布日期:2012-11-24
  • 作者简介:王胜朝,口腔医学博士、副教授。现任第四军医大学口腔医学院口腔预防科主任。兼任中华口腔医学会口腔预防医学专业委员会委员、陕西省预防医学会口腔保健专业委员会副主任委员、《牙体牙髓牙周病学杂志》编委、《实用口腔医学杂志》及Journal of Oral Science审稿人。主要科研方向是龋病与牙髓病防治的应用基础研究。承担国家自然科学基金面上项目2项,陕西省攻关课题2项。发表论文40余篇,其中SCI收录论文4篇。参编专著3部。
  • 基金资助:

    基金项目:陕西省卫生科研项目(2010D51)和社发攻关项目(2011K12-40)

Effects and application of oral probiotics on dental caries prevention

WANG Sheng-chaoXU Hao-kun.   

  1. Department of Preventive Dentistry,School of Stomatology,The Fourth Military Medical University,Xi’an 710032,China
  • Online:2012-10-15 Published:2012-11-24

摘要: 口腔内已知细菌种类多达700余种,多种微生物属于益生菌(probiotics)。近年研究发现,益生菌能够竞争性抑制口腔致病菌黏附和定植、中和致病毒素,还可能通过调节机体免疫反应维持口腔中的菌落平衡,从而对龋病、牙周病等的防治发挥积极的作用。特别是益生菌对龋病预防作用取得了更多证据支持,同时口腔益生菌也得到一定商业化开发应用。本文就口腔益生菌的防龋作用与应用做一回顾和展望。
关键词:                 Abstract:        Keywords:

关键词: 口腔益生菌, 龋病预防

Abstract: More than 700 species of human oral bacteria have been found. Many of them belong to probiotics. Oral probiotics have been found to be able to compete with pathogenic microorganisms for adhesion sites,to antagonize these pathogens or to possibly modulate the host’s immune response. Evidences to date suggest that oral probiotics could be useful in preventing and treating oral infections,including dental caries,periodontal disease. Here we summarize the currently available data on the potential benefits of probiotics for denal caries prevention,as well as on the appliation of oral probiotics.

Key words: oral probiotics, caries prevention

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