中国实用口腔科杂志

中国实用口腔科杂志 ›› 2012, Vol. 5 ›› Issue (01): 41-43.

• 论著 • 上一篇    下一篇

可吸收胶原生物膜用于齿槽裂植骨修复临床疗效研究

  

  1. 广东省口腔医院 南方医科大学附属口腔医院，广州  510280
  • 收稿日期:2011-08-19 修回日期:2011-11-10 出版日期:2012-01-15 发布日期:2012-02-28

  • Received:2011-08-19 Revised:2011-11-10 Online:2012-01-15 Published:2012-02-28

摘要：

目的    探讨可吸收性胶原生物膜应用于齿槽裂植骨修复的临床效果。方法    选择2006—2009年在广东省口腔医院口腔颌面外科就诊的单侧齿槽裂患者108例，年龄9 ~ 13岁，随机分为2组。对照组60例单纯应用髂骨松质骨行植骨修复，试验组48例应用髂骨松质骨加可吸收胶原生物膜覆盖行植骨修复。术后1周及3、6、12个月行X线检查。结果    试验组植骨成活率和临床成功率（97.9%、79.2%）高于对照组（86.7%、58.3%），差异有统计学意义（P < 0.05）。结论    自体髂骨加可吸收胶原生物膜联合应用于齿槽裂植骨修复中，可有效提高植骨成功率，为后续治疗提供更好保障，值得临床推广。

关键词: 齿槽裂, 骨移植, 胶原生物膜, 自体骨

Abstract:

Objective    To investigate the clinical effects of absorbable collagen bio-membrane in the bone graft repair of alveolar cleft. Methods    Totally 108 patients aged 9-13 years with alveolar cleft who were treated in Guangdong Provincal Stomatological Hospital between 2006 to 2009 were included，and they were divided into control group（n = 60）using cancellous tissue of iliac bone and experimental group（n = 48）using cancellous tissue of iliac bone combined with absorbable collagen bio-membrane. Patients were followed up postoperatively，radiographs taken in 1 week，3，6，12 months and their treatment effect evaluated. Results    The overall survival rate and the clinical success rate of the bone graft in experimental group were 97.9% and 79.2%，which were higher than those in control group（86.7 % and 58.3%）. There was significant difference between the two groups（P < 0.05）. Conclusion    The application of cancellous tissue of iliac bone combined with absorbable collagen bio-membrane is a better method in the bone graft repair of alveolar cleft.

Key words: alveolar cleft；bone graft；collagen bio-membrane；autogenous bone