中国实用口腔科杂志

中国实用口腔科杂志

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局部应用牙周抑菌剂治疗急性牙龈炎、牙周炎疗效观察

秦立芳1，李林可2   

  1. 1.北京市海淀区中医医院口腔科，北京 100086;2.北京中医药大学附属东直门医院口腔科，北京 100021

  • 收稿日期:2009-05-21 修回日期:2009-09-15 出版日期:2009-10-15 发布日期:2009-10-15

  • Received:2009-05-21 Revised:2009-09-15 Online:2009-10-15 Published:2009-10-15

摘要：

摘要：目的 探讨自制复方中药制剂——牙周抑菌剂局部用药治疗急性牙龈炎、牙周炎的临床疗效。方法 将 2006年10月至2008年4月在北京市海淀区中医医院口腔内科门诊就诊的急性牙龈炎、牙周炎患者24例（170颗患牙）随机将患者左右两侧患牙分为试验组（牙周抑菌剂组，85颗牙齿）和对照组（碘甘油组，85颗牙齿），分别局部给牙周抑菌剂或碘甘油进行治疗。治疗前后对患牙牙周相关指标［牙周探诊深度（PD）、牙龈指数（GI）、龈沟出血指数（SBI）、菌斑指数（PLI）］进行测量，并对两组治疗前后、两组治疗后的牙周相关指标及有效率情况进行比较。结果 用药前后试验组、对照组各项指标自身比较，差异均具有统计学意义（均P＜0.01）。用药后两组PD（t =3.257，P＜ 0.05）、GI（χ2 =7.673，P＜0.05）、SBI（χ2 =9.899，P＜0.05）差异均具有统计学意义，牙周抑菌剂较碘甘油对牙周急性炎症者的PD、GI、SBI改善更明显;用药后试验组和对照组PLI差异无统计学意义（χ2 =3.026，P > 0.05）。试验组总有效率达75.30%，对照组总有效率为52.94%，两组差异有统计学意义（χ2 =12.528，P < 0.01）。结论 牙周抑菌剂较碘甘油对牙周急性炎症的消炎抑菌作用更优。

关键词: 急性牙龈炎, 急性牙周炎, 牙周抑菌剂

Abstract:

Abstract：Objective To evaluate the clinical effect of subgingivally administering the Chinese medicine preparation-periodontal antimicrobial agent in the auxiliary treatment of acute gingivitis and periodontitis. Methods A total of 24 cases of acute gingivitis and acute periodontitis（170 teeth）were randomly divided into two groups：the treatment group（85 teeth）and the control group（85 teeth）. The two groups were given periodontal antimicrobial agent or iodine glycerin respectively. Measure the related indices before and after treatment，including PD，SBI and PLI，and compare these indices and the effects. Results Indices of both groups showed significant improvement（P < 0.01） compared with baseline. After applying the two ointments ， all indices（GI， PD， SBI） of the two groups showed significant differences，including PD（t =3.257，P < 0.05），GI（χ2 =7.673，P < 0.05） and SB（χ2 =9.899，P < 0.05）. The group treated with periodontal antimicrobial agent had statistically and significantly greater reduction than the control group with iodine glycerin， but PLI of the two groups showed no difference（χ2 =3.026，P > 0.05）. The effective rate was 75.30% in the treatment group and 52.94% in the control group，and the two groups showed significant differences.（χ2 =12.528，P < 0.01）. Conclusion Administration of Chinese medicine preparation-periodontal antimicrobial agent at subgingivally periodontal pocket as the auxiliary treatment of acute gingivitis and periodontitis can get good clinical results.

Key words: acute gingivitis, acute periodontitis, periodontal antimicrobial agent