关键词: 瑞芬太尼, 丙泊酚, 清醒插管, 血流动力学

Abstract: Remifentanil vs propofol continuous infusion for awake nasal intubation of difficult airways. HE Xiao-fan， ZHANG Qian， JIN Xuan-yu. Department of Anesthesia， School of Stomatology， China Medical University， Shenyang 110002， China
Abstract : Objective To compare the safety and availability of remifentanil and propofol for awake intubation of difficult air ways. Methods We recruited 24 ASA I-II patients， who were undergoing awake intubation after superficial anaesthesia . Patients were randomized to one of the two groups， Group Ⅰ （n=12） received remifentanil continous infusion 0.075 μg／（kg·min） after a bonus injection of 0.75 μg／kg， and Group Ⅱ （n=12） received propofol 6μg／（kg·min） after bonus injection of 0.5 mg／kg. Primary outcome measures were conditions（HR， SBP，DBP， SpO2） achieved at pre-intubation， intubation through choana， during intubation and post-intubation. Results All the patients completed awake intubation . Haemodynamic change in group I were significantly fewer than in group II. Conclusion After superficial anaesthesia， awake intubation is better achieved by continous injection of remifentanil than propofol; haemodynamic changes are fewer .

Key words: remifentanil, propofol, awake intubation, haemodynamic changes