关键词: 布比卡因, 左布比卡因, 拔牙, 磨牙

Abstract: Comparison of levobupivacaine and bupivacaine in the extraction of impacted mandibular third molars: a cross-over trial . LI Xiang-xin. The First People’ Hospital of Lianyungang ， Lianyungang 222002， China
Abstract: Objective To determine the duration and the effects of levobupivacaine and bupivacaine in the extraction of the impacted mandibular third molars. Methods Twenty patients with bilateral impacted mandible third molars were selected. Levobupivacaine and bupivacaine were injected into the two sides respectively. The rate of analgesia was judged by the patients and the operator. The onset time of analgesia and its duration and the postoperative side effects were observed and compared. Result Pain intensity was rated by the operator on a faces pain scale （FPS）. The average FPS was 1.95±1.10 and 1.90±0.91 in group LB and B respectively （P > 0.05）. The patients themselves evaluated their pain on a numerical rating scale （NRS）. The average NRS was 2.15±1.23 and 2.10±1.55 in group LB and B respectively （P > 0.05）. The average onset time was （3.64±0.50） min and （3.73±0.44） min respectively （P > 0.05）. The duration was （8.80±1.67）h and （7.48±1.41）h respectively （P < 0.05）. No side effects were observed in both groups. Conclusion Levobupivacaine is safe and effective in the extraction of the impacted mandibular third molars. It is a long-lasting local anesthetic with effective post-operative analgesia.

Key words: bupivacaine, levobupivacaine, tooth extraction, molars