关键词: 3D打印个性化钛网, 引导骨再生, 复杂牙槽骨缺损, 假骨膜

Abstract: Reconstructing complex alveolar bone defects is a challenge in oral implant therapy，and traditional methods such as guided bone regeneration，onlay block bone grafting，and distraction osteogenesis have limitations. The 3D-printed individualized titanium mesh（3D-PITM），which combines digital design and additive manufacturing technology，can precisely match the bone defect area，significantly shorten surgical time，reduce the risk of titanium mesh exposure，and achieve personalized alveolar bone augmentation. This article introduced the application process of 3D-PITM supported guided bone regeneration（3D-PITMs GBR）in the reconstruction of complex bone defects，including titanium mesh design，incision design，recipient site management，titanium mesh fixation，wound closure，and postoperative management. It also discussed factors affecting osteogenesis，such as appropriate augmentation design，exposure and precise positioning of the 3D-PITM，and selection of bone graft materials. The 3D-PITMs GBR technology is highly predictable and is suitable for all types of alveolar bone defects，especially showing excellent performance in the treatment of complex bone defects. It is expected to play a greater role in clinical practice in the future.

Key words: 3D-printed individualized titanium mesh, guided bone regeneration, complex alveolar bone defects, pseudo-periosteum