关键词: 具核梭杆菌, 结直肠癌, 炎症性肠病, 急性阑尾炎

Abstract: Fusobacterium nucleatum（F. nucleatum），a Gram-negative obligate anaerobe bacterium，has been proved to be one of the most important pathogens of periodontal disease. Recent studies have shown that F. nucleatum is related to a variety of systemic diseases，and the relationship between F. nucleatum and the intestinal disease has attracted wide attention. This study is to summarize the research progress in the relationship between F. nucleatum and intestinal diseases，including inflammatory bowel disease，acute appendicitis and colorectal cancer，in clinical and pathological aspects.

Key words: Fusobacterium nucleatum；colorectal carcinoma；inflammatory bowel disease；acute , appendicitis