Abstract:

Abstract： Objective To investigate the effect of bionic electrical stimulation therapy in improving the pregnancy outcome of intrauterine insemination (IUI). Methods 96 patients (146 IUI cycles) with both fallopian tube unobstructed between March 2012 and May 2013 were recruited in this study. They were divided into two groups according to whether the bionic electrical stimulation therapy was used during the IUI cycle. Results A total of 34 patients with 42 IUI cycles and 62 patients with 104 cycles were included into the study group and the control group,respectively. The pregnancy rate per cycle of the study group was significantly higher than that of the control group (28.6% versus 10.6%, P<0.05). In addition, both the mean age and the duration of infertility were higher in the study group when compared with the control group. Conclusion Bionic electrical stimulation therapy may be effective on improving the pregnancy rate of IUI. Further studies are needed in this area to investigate its effectiveness.

Key words: bionic electrical stimulation therapy, intrauterine insemination, pregnancy rate

摘要：

目的 探讨仿生物电疗法在人工授精周期治疗中的应用价值。 方法 中山市人民医院生殖专科将仿生物电疗法应用于宫腔内人工授精（intrauterine insemination ，IUI）治疗，自2012年3月至2013年5月共完成34例42周期为研究组，选择同期条件相似的普通人工授精62例104周期为对照组。比较两组的妊娠情况。 结果 研究组女方平均年龄(31.6±4.5)岁，临床周期妊娠率28.6%。对照组女方平均年龄(29.3±4.4)岁，临床周期妊娠率10.6%。两组间促排周期比、不孕病因构成比、精液处理后精子情况、精子回收率等情况比较，差异无统计学意义（P＞0.05）。研究组女方平均年龄及不孕年限均显著高于对照组（P＜0.05），研究组临床周期妊娠率显著高于对照组（P＜0.05），差异有统计学意义。结论 在双侧输卵管通畅的人工授精治疗中应用仿生物电疗法可提高周期妊娠率。

关键词: 仿生物电疗法, 宫腔内人工授精, 妊娠率