Abstract: Considering the causes and potential risks of membrane rupture，induction of near-term and full-term premature rupture of membranes is of more positive significance than expected treatment. All PROM patients without contraindication to vaginal delivery may be considered for induction of labor within 2 to 12 hours or 24 hours after rupture of the membrane. Oxytocin，misoprostol，denoprostol，and mechanical methods can be used for induction of labor in patients with PROM. However，attention should be paid to the exclusion of infection，pelvic imbalance and other unsuitable conditions for vaginal delivery before induction，and more appropriate methods should be selected according to the patient's birth times and cervical Bishop score. In the process of induction of labor，we should also pay attention to the dynamic assessment of maternal and fetal conditions and progress of labor，and conduct individualized management.