中国实用妇科与产科杂志

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脂代谢和脂肪酸代谢与子痫前期

  

  1. 北京大学第三医院妇产科,北京 100191
  • 出版日期:2018-09-02 发布日期:2018-09-07
  • 通讯作者: 杨孜
  • 基金资助:

    北京市科技重大专项首都临床特色应用与成果推广(Z171100001017231)

Lipid and fatty acid metabolism disorders and preeclampsia.

  1. Department of Obstetrics and Gynaecology,Peking University Third Hospital,Beijing 100191,China
  • Online:2018-09-02 Published:2018-09-07

摘要:

子痫前期是母体在多因素、多机制和多通路作用下的综合征表现形式。孕前及孕期的脂代谢和脂肪酸代谢异常在某些子痫前期发生发展中发挥了重要作用。认识脂代谢和脂肪酸代谢相关遗传、环境、营养及基础疾病因素与子痫前期的关系,更利于深入理解子痫前期多因素、多机制、多通路的发病机制。

关键词: 脂代谢, 脂肪酸氧化, 急性动脉粥样硬化, 子痫前期

Abstract:

Preeclampsia is a syndrome manifestation due to multiple factors,multiple mechanisms,and multiple pathways.Abnormalities of maternal lipid metabolism and fatty acid metabolism before pregnancy and during pregnancy play an important role in the development of some preeclampsia. To understand the effects of genetic,environmental,nutritional factors and the effects of basic and underlying diseases on lipid metabolism and fatty acid metabolism associated with preeclampsia helps to get a deep understanding of the pathogenesis of multiple factors,multiple mechanisms,and multiple pathways in preeclampsia.

Key words: lipid metabolism, fatty acid oxidation, acute atherosis, preeclampsia

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