关键词: 抗磷脂抗体, 抗磷脂综合征, 抗心磷脂抗体, 抗&beta, 2-GP1抗体, 复发性流产

Abstract:

Abstract：Numerous studies show that antiphospholipid antibodies can cause recurrent miscarriage, unexplained recurrent miscarriage associated with antiphospholipid antibodies are antiphospholipid antibody syndrome scope. The studies showed that pathogenesis  of antiphospholipid antibodies including placental hypercoagulable state, thrombosis and direct damage of trophoblast cell,could lead to miscarriage. Treatment for antiphospholipid antibody-positive patients with recurrent miscarriage could be short course and individualized.The dose and duration of aspirin, adrenal corticosteroids and low molecular weight heparin therapy should be adjusted ,according to antiphospholipid antibodies, platelet aggregation and the D-D dimer level in the peripheral blood of patients. However, the diagnosis and treatment has yet to be further explored.

Key words: antiphospholipid antibodies；antiphospholipid syndrome；anticardiolipin antibodies；anti-β2- glycoprotein antibody； recurrent spontaneous abortion