妊娠期间大部分自身免疫性肝炎（AIH）患者可以维持病情稳定甚至缓解，但分娩后容易出现复发，严重者可出现肝纤维化、甚至肝硬化、肝昏迷。AIH患者发生妊娠不良事件的概率增加，如早产、流产等。AIH患者妊娠期间遵循肝病医生的医嘱将泼尼松减至最小剂量继续维持治疗。妊娠的AIH患者需要在产科和肝病医生的共同监护下，在妊娠期及产后密切随访。

Abstract: During pregnancy, most of autoimmune hepatitis (AIH) patients can maintain stable or even be relieved, but they are prone to have recurrence after delivery，and some of them may develop liver fibrosis, liver cirrhosis, and even hepatic coma.The occurrence rate of adverse pregnancy outcomes in AIH patients increased, such as premature birth, abortion and so on. AIH patients during pregnancy should continue to maintain prednisone treatment at a minimum dose according to the doctor’s guidance. AIH patients at pregnancy need to be closely followed up during pregnancy and postpartum by the obstetricians and hepatologists.