自身免疫性疾病是一种免疫紊乱状态，要认识妊娠与自身免疫的相互影响，做好围产期管理，包括建立多学科团队、特殊的检验项目、个体化的药物治疗、计划性妊娠、重视产前检查、加强胎儿胎盘功能监护、适时终止妊娠和做产褥期处理等。

Abstract：Autoimmune disease is a situation of immune disorder, and realizing the interaction between pregnancy and autoimmune disease and taking effective measures during perinatal stage is essential to ensure a successful delivery. In brief, we should set up multi-disciplinary teams, do some special tests and make individualized drug treatment, make plans before pregnancy, attach importance to prenatal examinations, enhance fatal and placental monitoring, terminate pregnancy in a proper time and make managements during puerperium stage.