钙、维生素D与原发性骨质疏松症

doi:10.7504/fk2014040106

摘要/Abstract

摘要：

钙和维生素D是维护骨骼健康的重要的营养素，饮食中充足的钙和维生素D的摄入，是预防和治疗骨质疏松症的基础。许多人，特别是中老年人，是钙和维生素D缺乏的高危人群。因此，骨质疏松症的患者在开始考虑药物治疗的同时，也应该考虑充足的钙和维生素D的摄入，它是骨质疏松症治疗中的重要一部分，不能达到需要的水平时应该补充钙和维生素D的制剂。

关键词: 钙, 维生素D, 骨质疏松症

Abstract:

Abstract:Calcium and Vitamin D are the key important nutrients. Adequate dietary intake of them is the basis for the prevention and treatment of osteoporosis. Many people,especially the elderly are at high risk for calcium and vitamin D deficiency. So osteoporosis patients being considered for pharmacologic treatment should also be counseled on the importance of adequate calcium and Vitamin D as part of any treatment program for osteoporosis.If the required level are not reached,supplements should be used. 

Key words: calcium, Vitamin D, osteoporosis

中图分类号:

R711

黄琪仁. 钙、维生素D与原发性骨质疏松症[J]. 中国实用妇科与产科杂志, DOI: 10.7504/fk2014040106.

HUANG Qi-ren. Calcium,Vitamin D and osteoporosis[J]. Acta Metallurgica Sinica, DOI: 10.7504/fk2014040106.

参考文献

[1］ Reker RR,Lappe J,Davies K,et al. Characterization of perimenopausal bone loss: a prospective study[J]. J Bone Miner Res,2000,15: 1965-1973.

[2］ Nordin BE. Calcium and osteoporosis[J]. Nutritiom,1997,13: 664-686.

[3］ Dawson-Hughes B,Dallal GE,Krall EA,et al.A comtrolled trial of the effect of calcium supplementation on bone density in postmenopausal women[J]. N Engl J Med,1990,323: 878-884.

[4］ Dawson-Hughes B.Calcium and Vitnmin D nutrition needs of elderly women[J]. J Nutr,1996,126(4 suppl):1165S-1167S.

[5］ Heaney RP,Dowell MS,Hale CA,et al. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D[J]. J Am Coll Nutr,2003,22:142-146.

[6］ Bischoff-Ferrari HA,Giovannucci E,Willett WC. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcome[J]. Am J Clin Nutr,2006,84:18-28.

[7］ Chanpuy MC，Arlot ME， Duboeuf F，et al．Vitamin D3 and calcium to prevent hip fracture in elderly women[J]．N Engl J Med，1992，327：1637-1642．

[8］ Heike A,Bischoff-Ferrari HA,Walter C,et al.Fracture prevention with vitamin D supplementation:a meta-analysis of randomized controlled trials[J].JAMA,2005,293:2257-2264.

[9］ Bischoff-Ferrari HA,Willett WC,Wong JB,et al. Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysisi of randomized controlled trials[J]. Arch Intern Med,2009,169:551-561.

[10］ Bischoff HA，Borchers M,Gudat F,et al. In situ detection of 1,25-dihydroxyvitamin D3 receptor in human skeletal muscle tissue[J]. Histochem J,2001,33:19-24.

[11］ Bischoff-ferrari HA,Dawson-Hughes B,Willett WC,et al. Effect of vitamin D on falls: a meta-analysis[J]. JAMA,2004,291:1999-2006.

[12］ Murad MH,Elamin KB,Abu Elnour NO,et al. Clinical review: the effect of vitamin D on falls: a systematic review and meta-analysis[J]. J Clin Endocrinol Metab,2011,96:2997-3006.

[13］ Ricky F,Laurent D,Erich S,et al. Differential Effect of D-Hormone Analogs and Native Vitamin D on the Risk of Falls: A Comparative Meta-Analysis[J].Calcif Tissue Int,2008,82:102-107.

[14］ Gallagher JC. The effects of calcitriol on falls and fractures and physical performance tests[J]. J Steroid Biochem Mol Biol,2004,89-90:497-501.

[15］中华医学会骨质疏松和骨矿盐分会.原发性骨质疏松症诊疗指南(2011年)[J].中华骨质疏松和骨矿盐疾病杂志,2011,4(1):2-17.

[1]	黄淑晖,刘淮. 钙对孕产妇和围生儿骨健康的影响[J]. 中国实用妇科与产科杂志, 2014, 30(8): 643-647.
[2]	马颖. 中老年女性骨质疏松症的其他治疗方法[J]. 中国实用妇科与产科杂志, 2014, 30(5): 347-351.
[3]	颜建英，廖秋萍，刘青闽，徐榕莉，黄晓燕，林顺和，陈文祯，罗美瑜. 子宫平滑肌大电导钙激活钾通道α、β 亚基表达与产后出血的关系[J]. 中国实用妇科与产科杂志, 2014, 30(2): 113-117.
[4]	高英1）谷香珍2）周卫卫2）白桦2）李文杰1）张青梅1）郭春艳1）张允络3）. 早产儿脑损伤与围生期感染的相关指标测定及意义[J]. 中国实用妇科与产科杂志, 2005, 1(6): 379-380.